Q3 2017 Lab News
Ken Lyon and Richard Young along with SchillerLAB collaborators published their paper on Minimotif Miner 4.0 in NAR. Minimotif Miner now has a billion minimotif entries. This is Ken's second first author and a third publication in our lab. Richard was awarded AWS Research Grant to pursue his undergraduate honors thesis. Surbhi Sharma attended a NIH Sponsored Workshop on Targeted Quantitative Proteomics and received a NV-INBRE Proteomics Service Award for her multiplex labeling mass-spectrometry experiment. She was selected to present at the Graduate Research Showcase during UNLV research week and also received a scholarship for the same. She was also recognized as one of the high achieving students and was awarded the first roll-out Medallion of Honor by UNLV Graduate College. Dr. Schiller gave a keynote talk at NEVADA-INBRE meeting on personalized medicine. Dr. Schiller also launched his new company Food Genes and Me that offers a personalized diet recommendation based on the user's genome. Read NIPM's accomplishments during this quarter in NIPM's newsletter.
Q2 2017 Lab News
Schiller Lab welcomes several new members: Kenneth Estimos, Lab Manager; Danielle Eames and Lindsay Buczek, undergraduate researchers and Atoshi Banerjee, Post Doctoral Fellow who will work with our post-doc, Ronald Benjamin Babu, on his project. Several undergraduate researchers also graduated and some came back to share the news about their next ventures: Nemanja Novakovic joined Medical School at University of Michigan; Henrik Babajanyan and Kiran Mathew joined UNR School of Medicine; Roxanne David, UNLV Dental School; Horacio Guerra was accepted with full scholarship to the first class of the UNLV School of Medicine and Victoria (Tory) joined the MS program at UNLV School of Public Health. Saragrace Trimidal defended her undergraduate honors thesis. She worked on several projects in the lab including, NHEJ and CMD. Nemanja Novakovic was acknowledged as one of the outstanding UNLV graduates during Spring 2017 commencement ceremony. Surbhi Sharma, graduate student, was placed 1st in her session at GPSA Research Forum, presented her work in oral and poster formats at Gordon Research Seminar on Proteins and a poster at Gordon Research Conference on Proteins. She also received GPSA Sponsorship funding for Fall 2017 and was invited to be one of the 8 student delegates to represent UNLV Research at the NV Capitol. Dr. Schiller gave a talk on HIV during HIV and AIDS awareness week hosted by CSUN, UNLV. Also see what kept Dr. Schiller busy through NIPM's quarterly newsletter.
Q1 2017 lab news
Congratulations to Schiller LAB undergraduate researcher Nemanja Novakovic who received the Distinguished Nevadans, Regents' Scholars award. Nemanja worked on the C-terminome project in the Schiller LAB. He was trained by graduate student Surbhi Sharma and has coauthored three papers in our lab. The LAB also presented its research in a number of oral presentations and posters at the annual Nevada Institute of Personalized Medicine Retreat. Pascal Nilsson, Surbhi Sharma, and Ronald Ben, all gave short talks. Sara Trimidal, Jacklyn Newsome, and Ken Lyon also presented posters. The image shows a very pleased businessman from the public looking at Pascal's poster. Congrats to Surbhi Sharma, who received a NIH Nevada INBRE proteomics service grant.
Q4 2016 lab news
Surbhi Sharma received a Graduate & Professional Student Association for her work this semester. The Schiller Lab launched a startup company called Heligenics this quarter. See article.
Q3 2016 Lab news
Nemo Novokovic is doing his undergraduate Honors Thesis in the SchillerLAB working on the C-terminome with graduate student Surbhi Sharma. Nemo is one of this years recipients of the CSUN Undergraduate Research Fellowship. He has already been involved in cloning over 100 C termini into a Tap-tag system for mass spec analysis. Dr. Schiller was interviewed about the Nevada Institute of Personalized Medicine at the Las Vegas Downtown Podcast .
Q2 2016 lab news
Dr. Schiller was featured on the UNLV Research Video.
Q1 2016 lab news
Featured graduate student of the quarter, Surbhi Sharma publishes her first paper on the C-terminome. This is the first published paper on this new -ome. See the C-terminome webpage on bio-toolkit.com. Surbhi also won the GPSA service award for her role as Graduate Student and Professional Association (GPSA) president in 2015-2016. Dr. Schiller is recognized for his mentorship with the 2016 GPSA mentor award. A team of SchillerLAB undergraduate researchers led by Pascal Nilsson Dimarco wins a poster award at the Undergraduate Research Forum for their poster presentation on Nutrigenetics. The Schiller LAB is now featured on the UNLV undergraduate Research webpage Many Schiller lab student and Dr. Schiller present their research at the 2016 Nevada Institute of Personalized Medicine retreat. SchillerLAB undergraduate student Nemanja Novakovic was featured in a UNLV news article.
Q4 2015 lab news
Article about HIV TALEN research in the Rebel Yell and on KNPR SchillerLAB undergraduate student Kiran Mathews was featured as one of the outstanding UNLV graduates. Dr. Schiller gave a talk about Personalized Medicine at the local chapter of the Science Cafe. See the video on YouTube. Dr. SChiller also gave advise to graduate students at a GPSA event: YouTube video.
SchillerLAB gene editing work on HIV featured on NBC channel 3, Fox channel 5, a UNLV news release, Medical Xpress, Drug Discovery & Development Magazine , R&D Magazine, and on the front page of the Review Journal Newspaper this July. We also welcome two new graduate students to the lab, Omo Igbinedion and Jacky Newsome. Joining them are new postdoctoral fellow, Ron Benjamin. The lab also received a new NIH grant to work on our chimeric minimotif decoy biotechnology. Our lab is now listed as part of the UNLV Microbiology group. SchillerLAB students have outreach day with students organized by the American Society of Microbiology (see picture).
Q2 2015 lab news
SchillerLAB publishes a paper using TALEN technology to damage integrated HIV provirus. See published paper in PLoS ONE. See videos about our HIV research on our NIPM YouTube Channel and in a UNLV documentary soon to be released. In June our paper on the role of minimotifs in human adaptive evolution was published in Nucleic Acids Res. Undergraduate student Ken Lyon was first author on this paper. In other news, graduate student Surbhi Sharma was voted the next president of the UNLV Graduate Professional & Student Association . Kiran Mathews successfully defended her honors thesis project in the SchillerLAB. We also congratulate undergraduate student Clara Liu, who received an NIH Nevada INBRE summer fellowship. For updates on the new Nevada Institute of Personalized Medicine, see our website with links to a YouTube Channel and Twitter feed' Dr. Schiller is the Executive Director of this Institute. The SchillerLAB also bids farewell to Horacio Guerra who is moving on to graduate school at UCSD. Horacio received 4 research grants and had several papers including a co-firstauthored paper mentioned above. Dr. Schiller discusses the new Nevada Institute of Personalized Medicine on KNPR radio on June 15, 2015 (9:04 AM; see link to broadcast).
Q1 2015 news from SchillerLAB
Oniel Toledo and Surbhi Sharma from the Schiller Laboratory of Applied Bioinformatics (SchillerLAB) complete the beta-version of the C-terminome website. This quarter also saw the official launch of the Nevada Institute of Personalized Medicine (NIPM) led by Martin Schiller as Executive Director. The launch includes an Inaugural event with keynote talk by James Lupski, release of the NIPM website, and a front page article in the Las Vegas Sun newspaper. Also this month Dr. Qing Wu from the Mayo Clinic was hired into NIPM as a new faculty member.
November - December 2014 year wrapup
Graduate Student Surbhi Sharma participated in the first UNLV graduate student Rebel Slam competition and made it to the finals! I though she should have one ( a little bias here?). See a YouTube video of her 3 minute presentation and see what you think. We bid fellow Christy Strong farewell. She is now a faculty member in the UNLV School of Life Sciences and plans to continue collaboration on projects she developed in the lab. A feature article on some work in the Schiller lab is featured in the Desert Companion Magazine ; see pages 62-63.
September - October 2014 news
Version 1.32 of the new HIV ontology was released on the Bioportal website . We congratulate postdoctoral fellow Christy Strong who will become a Assistant Professor on January 1, 2015. Our patent on using Gene editing therapy to damage the latent HIV proviral DNA with TALENs was published published patent link SchillerLAB submits a new patent on chimeric minimotif decoy technology. Welcome Megan Svarz, who was hired as the new program coordinator for the Nevada Institute of Personalized Medicine (NIPM). Dr. Schiller has continued his duties as Director of this new Institute. We also welcome John Minnick, who will be the Business Development Officer for NIPM.
The grant fairy visited the Schiller lab. The lab was awarded a small grant to use a new algorithm in a GWAS analysis of Alzheimer's disease. We also were awarded a grant by NIH to continue building HIVToolbox. Also this month Marty became the Executive Director of a new research institute at UNLV. There will be more news about the Quantitative Health Sciences initiative in the coming months. We also welcome several new undergraduates to the laboratory including Rick Young, Govind Pathak, and Scott Fireoved.
May-June 2014 updates
The SchillerLAB publishes a paper on HIVToolbox2 . See a video about GoMAP for the lay person . The lab received a new NIH grant award to continue work on HIVToolbox. We have renamed our lab to SchillerLAB which is an abbreviation for the the Schiller Laboratory of Applied Bioinformatics. We wish Caleb Albornoz good luck as he leaves the lab to work for Caesars Entertainment. This month Dr. Schiller and postdoctoral fellow Dr. Christy Strong presented and the Intermountain West Clinical Translational research meeting.
Congratulations to Kiran Mathews in the lab you was awarded a Sigma Xi grant to develop a new type of genetic screen. The schillerlab publishes a paper on GoMAP . See a video about GoMAP for the lay person . Ken Lyons submits a first-authored paper as an undergraduate. This paper examined how minimotifs vary in the human population.
Schillerlab starts a new collaboration with the Jeff Kinney, UNLV Supercomputing Center and Ruvo Center for Brain Health studying minimotifs and sets of SNPS involved in Sporadic Alzheimer's disease. The project was funded by a seed grant from the Intermountain West Clinical Translation Research Grant from NIH. We Welcome Caleb and Bryan, who are Computer Science Undergraduates who have started on this work. The schiller lab releases version 1 of the HIV Ontology. This is part of the Infectious Disease Ontology and the lab is now a member of the IDO consortia.
Schiller lab participates in the Rebel STEM academy and we get our Radiation Use license. Surbhi Sharma will be doing several biosynthetic labeling experiments. David Sargeant completes the xReader Android app. Taecan LLC startup it back on track and recruiting investment. Our president decides to leave UNLV :-(. Marty helps write the UNLV Knowledge Fund proposal in Quantitative Health Sciences which is recommended for funding.
Anike Bill starts graduate school in the Schiller lab. She will be continuing work on the Kalirin- TrkA interaction which has become more interesting considering that Anti-NGF antibodies are showing promise as a new class of anagesics. The Schiller lab was awarded an NIH grant to study the C-terminome. Dr. Schiller does a spot for the new UNLV Research Files UNLV Research Files TV show that recently aired.
July - August 2013 - marriage report and Dr. Schiller on Channel 3
Postdoctoral Fellow Chirsty Strong was married this month. Best wishes. We also congratulate Surbhi Sharma who passed on qualifying exams. Best wishes to Sean Williams and Justin Limtong, who are off to med school. Kiran Mathews and Horacio Guerra present posters for their work this summer at the UNLV Undergraduate Research day. Dr. Schiller 5-part interview series with Jim Rogers airs on channel 3 Inside Nevada . Congrats to Surbhi Sharma, who passed her Ph.D comprehensive exam.
May – June, 2013, SchillerLab on TV
Two student from the Schiller lab, Anike Zalyte and Travis bill got married this month. We wish them well and look forward to Anike who will be entering graduate school this fall to continue her research on receptor tyrosine kinase activation mechanisms. Dr. Schiller does a 5-part interview series with Jim Rogers on Inside Nevada (Channel 3) to appear August, 2013. Horacio Guerra’s research in the Schiller lab was featured by the UNLV foundation. See article. Schillerlab receives a grant to develop an experimental screen for minimotifs. Christy Strong, postdoctoral fellow will lead this project. We wish David Sargeant well, who has taken a leave of absence from the lab to deal with health issues.
March – April, 2013, Schillerlab students get funded!
Congratulations to Surbhi Sharma for receiving a Sigma Xi grant and honorable mention for her presentation the UNLV GPSA. Horacio Guerra and Kiran Mathews received Nevada INBRE Fellowships to support their projects in the lab – congrats. Dr. Schiller gave a seminar about SchillerLab Biotechnology at NevBio.
January-February -Schiller Lab spawns a startup company.
During the first couple months of 2013, the Schillerlab has launched Taecan LLC, a new startup company based on research performed at the University of Nevada Las Vegas. The mission of the comany is to accelerate reading, writing and learning. The company will commercialize the SciReader technology which has been filed for patent protection with the US patent office and is in the final stages or revision and review. The company will be releasing several new mobile apps and browser plugs for personal computers, the first release planned during the first quarter of 2013. Dr. Schiller will serve as the Chief Executive Officer and David Sargeant who will be graduating with a Masters in Computer Science will become the Chief Technology Officer. We have recruited a Board of Advisors comprised of several business leaders and are currently negotiating with experts in software marketing. Depending on these negotiation, we may be offering shares of the company for investment. Contact martin.schiller(at)xreaderapp.com For more information about the first product to be released check out xReaderapp.com. You can give our app prototype a try here. You can register to receive news when our product become available. Follow us on Twitter at Xreaderapp.
Also of note this month our HIVToolbox web application has been used >30,000 times now. Watch for release of HIVToolbox2 in the coming months with several new features and data updates.
Also of note this month our HIVToolbox web application has been used >30,000 times now. Watch for release of HIVToolbox2 in the coming months with several new features and data updates.
November -December 2012 - Advancing minimotif theory
As the use of Minimotif Miner approaches 50,000 searches in the next month or so, our lab now publishes a critical paper in the field of minimotifs that advances our theoretical understanding of specificity. There are over 100,000 papers on minimotifs that help define a consensus sequence expression or a position specific scoring matrix. In reality, using these expressions provide poor predictability with high false positive rates. In our PLoS One paper this week (Sargeant et al 2012), we identify the missing element of structure as a critical part of minimotifs definitions. in an example minimotif, when structure is added into the protein sequence based definition, we recapture almost all of the known specificity. We think this is a major step in our understanding of minimotif specificity. Shown to the left is a figure from the paper showing that many minimotifs blue have structures. This month we also congratulate undergraduate Horacio Guerra who received an NSF EPSCOR to continue his work in the lab on new types and applications of TALEN technology.
October 2012 - cool publication from the Schiller lab
This month a paper from our lab was accepted for publication in PLoS One . The paper identifies key deficiencies in the current practice in using consensus sequences and PSSMs to define short functional protein sequence motifs. The paper goes on to show that much of the specificity of the motif definition is lost because structure is not included. We then propose a new model and implementation where sequence, structure and function is used to define minimotifs. We think this will be a very influential paper as current theory about minimotifs considers sequence based definitions only and this produces poor predictability. There are ~100,000 published papers about these short functional motifs. Our new approach provide drastically increased accuracy on several test cases. Look for this paper to be published soon.
September 2012 News
Dr. Schiller was awarded the NevBio Top Research in Nevada award for 2012. New videos tutorials for HiDRA are now available. HIVToolbox exceeds 25,000 searches. Look for a new version in the coming months.
August 2012 in the Schiller lab
Undergraduates Karlyn Dobritch, Anike Zalyte, Horacio Guerra, and Carl Walsh completed their summer fellowships in the lab. They presented posters at the Undergraduate Research Day. Anike, Horacio, and Karlyn are continuing their projects. The lab also had a paper accepted in PLoS One that uses several sources of data to reduce false positive predictions of minimotifs. This is best performing algorithm thus far.
July 2012 Schiller Lab happenings
Martin Schiller was promoted to the rank of Professor. Marty presentation of new lab technologies to NevBio received a warm welcome. These technologies include a new approach for genome surgery; a patent application for this technology has been filed. Many thanks to UNLV IP attorney Mark Litman for his efforts in preparing the application. The Schiller Lab presented at the International AIDS meeting in Washington DC this month to present the labs work on HIVToolbox version 2 and HIVAtlas. Christy Strong presented a poster and David Sargeant presented a talk.
May - June 2012 lab update
Horacio Guerra, Karyln Dobritch, Lelani Wong, Anike Zaylte, and Carl Walsh have started their summer fellowship projects in the lab. We welcome Sarah Harris to the lab, a visiting scientists from Harvey Mudd College who is an expert on Electrical Engineering. Dr. Schiller gave a guest lecture on Bioinformatics to the College of Southern Nevada.
Congrats are in order to three students in our lab. Horacio Garcia received a NIDDK summer fellowship award to work in our lab this summer. Anike Zalyte and Karlyn Dobritch both received an INBRE NIH summer fellowship as well. Marty Schiller gave at talk at the University of Nevada Reno on Software tools for discovering new functions in proteins. This month papers on using genetic interaction to reduce false positive prediction of minimotifs (PMID: 22403687) and the structure of the DH1 domain of Kalirin (PMID: 22314704) were published. These were in collaboration with the Rajasekaran and Hoch groups, respectively. The Bio-toolkit is now active on Twitter.
January-February 2012 news
A paper in collaboration with Shawn Li and Edwin Wang was published in Genome Research. This paper shows that phosphotyrosine signaling minimotifs are much more prevalent in higher metazoans and suggest that minimotifs play a significant role in the evolution of multicellularity. The new update to Minimotif Miner was published in the annual Nucleic Acids Res. database issue. This paper also has corrections to our model for minimotifs. Marty will present and has help organize the 2nd IEEE International Conference on Computational Advances in Bio and Medical Sciences (ICCABS) held this February in Las Vegas. Marty will also present the Bio-tookit at the 2012 Metabolomics conference.
November-December 2011 news
The new release of Minimotif Miner 3 has ~300,000 minimotifs and a new filter algorithm that vastly reduces false positives. This paper will appear in the 2012 Nucleic Acids Research Database issue. Thus far, minimotif miner has now had ~43,000 searches performed. This month we are also releasing a prepublication version of our new HIVAtlas application. A paper reporting the structure of of the DH1 domain of Kalirin was accepted for publication
HIVToolbox is now used over 10,000 times. Martin Schiller was voted for promotion to Full Professor at the Departmental level. We welcome Sean Tuggle to the lab and bid farewell to Dorothea Maza, who is getting ready for Optometry school and also to Sandeep Deverasetty who is now working on a Genome sequencing project at UCLA (Sandeep's farewell shown). We also Welcome Astha Bajpai and Surbhi Sharma to the lab as new graduate students in the School of Life Sciences. We also are pleased to start a new collaboration with Dr. Ernesto Abel-Santos and his students Horacio Garcia and Mistry. They will be synthesizing some new lead compounds for treating HIV based on our bioinformatic based drug design.
August 2011 news
Andy Brooks and Max Olsen complete their summer projects and presented a poster at the Undergraduate Research Day. The picture to the left shows Andy describing his work to Dean Porter. Alex Navarro Harrison presented his summer project examining the TrkA Kalirin interaction at NIH. We are happy that Andy and Alex will be continuing in the lab. We also welcome our new collaboration with Dr. Ernesto Abel Santos and his students Horacio Garcia and Mistry Sabyasachi who are designing new HIV drugs designed by graduate student David Sargeant. It seems like former student Jay Vyas is having trouble completing his dissertation at the University of Connecticut. This comical video accurately documents the recent history of Jay's trials and tribulations in his ongoing effort working toward his Ph.D.
July 2011 news
HIVToolbox reaches 7500 searches in second month.
June 2011 news
We welcome three new students to the lab for summer fellowship on the REU/NSF and STEP UP/NIDDK programs at UNLV. Shown are Max Olsen who comes to us from Utah State University and Andy Brooks from RPI. Alex Navarro-Harrison is also working on a HIV-1 project in the lab this summer. Logan Lee is also back and will be working on building our BioPod data warehouse. Marty Schiller gave two seminars at the Western IDeA Scientific Conference on the Bio-toolkit and on the UNLV Grant Club. HIVToolbox usage passes 6000 searches during its first month after publication in PLoS One.
April-May 2011 News
HIVToolbox paper was published in PLoS One. Also we are pleased to announce that proteins structure links in the Protein Data Bank are now linked to HIVToolbox.
February-March 2011 news
We welcome soon to be Dr. Christy Strong to the lab who will be a postdoctoral fellow. We also welcome two new graduate students, Astha Bajpai and Subrhi Sharma who will be entering the School of Life Sciences graduate program this fall. Also we are pleased to announce that proteins structure links in the Protein Data Bank will be linked to HIVToolbox in their April/2011 release.
January 2011 - SciReader paper is accepted
Paper on SciReader is accepted, Lab has first annotation bootcamp to annotation data for OROMiner. Masters students Pat Gradie and Mike Rogers are leaving the lab to pursue jobs in industry - best wishes. We welcome undergraduate student Esra Nassar into the lab.
Schiller lab presents posters and talks at Rocky Mountain Bioinformatics Conference. Mike Rogers, MS student in computer science presented his work on ORO Miner. Dave Sargeant presented a poster on HIVToolbox, and Pat Gradie presented a poster on SciReader. Marty Schiller has a paper accepted on a new gene in Hearing in collaboration with the Hearing Consortia.
Collective news for September
We welcome several new Undergraduates to the lab including Nicki Cohen and Parris Crooks, and Emily Tamadonfar. We also received a new R01 grant from the National Institutes of Health with our collaborator (Sanguthevar Rajasekaran, PI of grant). This is to develop new algorithms for identifying minimotifs. Martin Schiller is teach Cellular and Molecular Biology this semester (BIO 196). We have submitted a new proposal to continue or HIVToolbox project. The HIVToolbox was released this month. See the new website from the virus icon.
Paper on protein-protein interactions and minimotifs published in Proteins
A paper in Proteins was just accepted. This paper describes a new filter in Minimotif Miner that has two purposes. You can now identify minimotifs that provide mechanisms for protein-protein interactions and can also filter minimotif predictions restricting them to proteins that are already known to interact in one of the 5 major protein-protein interaction databases. Marty will be teaching Cellular and Molecular Biology (BIOL 196) this semester. We would also like to thank our summer students Logan Li, Cory Russo, and Narineh Abadian. Logan will continue to help us build our data warehouse.
Paper on improved accuracy of minimotif prediction published in PLoS One
Our paper that uses cellular and molecular function from the Gene Ontology database was accepted for publication in PLoS One. We also welcome Tia Maza to the lab who is working on our model for HIV drugs and drug resistance. Also this month Mike Rogers has decided to do his Masters thesis work in our lab. Mike has already made significance contributions by building this website and developing and implementing the OROMiner model.
Paper on Mimosa accepted in BMC Bioinformatics
MimoSA is our new application for annotating Minimotifs. Congrats to first authors Jay Vyas and RJ Nowling, and to coauthors David Sargeant and Tom Meusburger for their first authored paper. Also this month, David Sargeant completes our 90 TB storage drive that will house our new Biowarehouse of biological data. Sandeep Deverasetty, David Sargeant, Patrick Gradie, Michael Rogers, and Chris Ross are starting to build this massive database.
SH2 Loops drive minimotif recogntion and bio-toolkit
Schiller lab publishes a paper with Shawn Li's group that was in Science Signaling. The new Bio-toolkit website was released. This brings all of the applications built by the Schiller and Gryk labs to a common website. A beta version of the human Anatomy, Histology, and Physiology database is released. Check it out !
The new Schiller lab webpage was released (schillerlab.bio-toolkit.com). Congrats and Thanks to Mike Rogers who designed this web page using Django. The renovation of the Bioinformatics lab is near completion. We were forced to keep a laboratory hood. We have named it "The Raymond DeFilippis Memorial Bioinformatics Hood"
Patrick Gradie presents his work
Pat Gradie presents his work on a new reading environment for scientific content and Prashant Singh presents the labs work on development of a integrated model for human anatomy, development and physiology. Marty to serve as grant reviewer for Israel Science Foundation.
Rennovation for new lab
Renovation on our new Bioinformatics lab starts. It is expected to be done by the beginning of April.
Patrick Gradie joins lab
Patrick Gradie, a previous undergrad collaborator who worked on Minimotif Miner release 2 joins lab as a software developer and plans to work on his Computer Science dissertation in the Schiller lab starting this fall. Dayne West got a job and moved on. We wish him well. Dayne completed several small projects related to our anticipated Stem cell database. Marty Started teaching his first class at UNLV on Great Biological Discoveries
UConn collaborators visit UNLV
Our University of Connecticut collaborators came to visit UNLV. This was a productive visit. Marty gave a short talk to the Nevada Board of Reagents on the labs research. Schiller and Shen labs propose a new Bioinformatics division in the School of Life Sciences, which is supported by several faculty in the department. Mike Rogers from Computer Science joins lab. Mike will work on our new website, the Bio-toolkit website and the Stem Cell databases
Thanksgiving party and presentation
The lab had a party for Thanksgiving. The laboratory presented a poster at the Human Proteome Organization on minimotif semantics. Marty went to the school of Life Sciences faculty retreat.
Sandeep Deverasetty joins lab
We welcome Sandeep Deverasetty to the lab who will be working as a computer programmer/Database Administrator. The laboratory also received and ARRA supplement for our grant on minimotifs in HIV. An article in the Las Vegas Sun featured the research of our lab.
David Sargeant joins lab
Dave Sargeant from Computer Science also joined the laboratory as a graduate student. Dave will work on the HIV Bioinformatics tool. We welcome a bunch of new undergraduates (Sahar Azim , Izua Alaniz , Caroline Chang , Farah Chowdhury , Keith Chung , Teinesha Irvey , Kate Keesling , Dave Lacambacal , Darlene Lara , Brian Lempa , Kyle Martin , Thomas Meusburger , Shruti Patel , Jacqueline Phan , Viraj Rathnayake , Brandon Roe , , Sherrie Serranno , Briana Sugihara , Thao Hoang , Paula Watts , Dayne West , Anike Zalyte , Stephanie Zobrist , Mike Rogers , Melissa Cope , Alex Spelman) to the new UNLV lab. We also moved into our new lab in WHI 119 and new Office in WHI 117.
Dr. Prashant Singh joins lab
Dr. Prashant Singh joined the lab to work on a Stem cell related project. Welcome aboard. We also released a new application called Venn (download page, publication). Our paper proposing a functional syntax for Minimotifs was also accepted. Congrats to student Jay Vyas who was the first author on both papers which were accepted on the same day, forever designated as JayDay. We formed a grant club of investigators at UNLV that meets weekly with the goal of increasing UNLV funding and resources.
Schiller lab moves to UNLV
The Schiller Lab has moved the University of Nevada Las Vegas in the School of Life Sciences.
Abstract on minimotif semantics accepted
An abstract for the HUPO 2009 congress on Minimotif semantics was accepted. Marty Schiller is serving on NIH study section for review of Challenge Grants. Marty will give a talk on the new release of MnM-HIV at the 23rd Annual Meeting of the Groups Studying the Structures of AIDS-Related Systems and Their Application to Targeted Drug Design sponsored by the National Institute of General Medical Sciences. The 2nd annual Gryk-Schiller beach party was a success. We enjoyed some Frisbee in the surf, shrimp and filet on the barby and some great company. For the second year running Jay Vyas from the Gryk lab came up short in the horse shoe competition losing to the rookie Marek Barwinski.
Schiller lab to move to UNLV
Schiller lab to move to UNLV this summer. We will miss all of our UCHC colleagues. Angel Villahoz Baleta presents the MnM-HIV website at the Center for Cell Analysis and Modeling.
MnM-HIV work presented
Angel Villahoz Baleta will present his work on the MnM-HIV website at the yearly MMSB retreat. MnM reaches 31,000 searches.
Alpha version of MnM-HIV running
Angel Villahoz Baleta gets a alpha version of MnM-HIV running. We are anticipating the first release soon. Several groups have agreed to share data with us for the MnM-HIV website. This includes the Los Alamos National Laboratory HIV database, the Stanford HIV Drug Resistance Database, Southern Research Institute HIV Protein-Protein Interaction database, and NIST HIV Structure database. We welcome these new collaborations. Shawn Li visits UCHC and give a talk on his work on minimotifs - he has presented some amazing work. Diana Finzi, our NIAID program officer has been a great asset in helping us on the MnM-HIV project- Thank you. We welcome Rinu Thomas to the lab who will be working on the new stem cell database project. Schiller/Gryk labs start a joint weekly journal club.
Talk at UNC
Marty Schiller gives talk at University of North Carolina, Charlotte, Bioinformatics Department. Marek Barwinski joins the lab and is starting a project solving the structure of several SH2 domains in collaboration with a long time collaborator in MMSB, Mark Maciejewski. Welcome Marek. Marty Schiller serves on the Connecticut Academy of Science Review Panel.
Talk at UNLV School of Sciences
Marty Schiller gives talk at University of Nevada Las Vegas School of Life Sciences.
New version of Minimotif Miner
A new version of Minimotif Miner was released MnM 2. The new release was published in the Database issue of Nucleic Acids Research. Jay Vyas and Krishna present their progress talks in the MMSB department.
Collaborative grant received
Lab receives a collaborative University grant with Drs. Craig Nelson at the University of Connecticut and Michael Gryk, a long time collaborator in the MMSB department. This goal of this seed grant is to develop a stem cell database.
Lecture at Biology Symposium
Marty Schiller gives talk on motifs and the New England Structure Biology Symposium .
Angel Villahoz Baleta joins lab
Angel Villahoz Baleta joins the laboratory to work on the new Minimotif miner HIV website. Angel comes to us from the Bioinformatics department at the University of Alabama whre he received a Masters. Debbie Jiang and Matt had a good time in their summer lab fellowships. We all wish them well. People (from left to right) Mike Gryk, Jay Vyas, MArty Schiller, Debbie Jiang, Matt Babcock, Krishna Kadaveru, Sonali Kadaveru.
Published in Experimental Cell Research
Paper on the role of Kalirin spectrin repeats published in Experimental Cell research and listed as a featured article. Marty was elected to Research Council. RJ Nowling, finishes his sucessful summer project to leave us and, yes, study dolphin fins. He will be back. First Schiller-Gryk lab summer beach party at Rocky Neck State Park was a lot of fun. Some Pics are below. The Krishna-Jay horseshoe grudge match was won by Krishna (middle pic), Jays horseshoe rolling technique will need some work. As the loser, Jay will contribute to the general lab fund for buying a summer beach house for next year.
New members for Summer
Matt Babcock and Debbie Jiang join the lab for the summer to work on the relationship of Kalirin and TrkA. Lab is awarded Grant from the National Institute of Allergy and Infectious Diseases to identify potential motif drug targets in HIV (R21AI078708-01)
RJ Nowling joins lab
RJ Nowling, joins the lab to work on an interface to the expert system for annotating motifs in Minimotif Miner.
Minimotif Miner presented at retreat
Jay Vyas and Marty Schiller present Minimotif Miner projects at the Molecular, Microbial, and Structural Biology retreat. Krishna Kadaveru presented his poster, and Martin Schiller was a Co-organizer of this event with Asis Das.
Short Functional Motifs paper accepted
Our review article on short functional motifs in human disease was accepted for publication in Frontiers in Bioscience. Also Schiller lab joins with the Gryk and Maciejewski labs to form the Biological System Modeling Group.
Shahana Abdullah joins lab
Shahana Abdullah joins the lab.
Martin Schiller - Associate Professor
Martin Schiller gets promoted to Associate Professor
Krishna Kadaver joins lab
Krishna Kadaveru joins the lab. Go Krishna!
Minimotif Miner covered in Biotechniques
Release of our Minimotif Miner website was covered in the Biotechniques.
Jay Vyas joins lab
We would like to welcome Jay Vyas who will be working on TrkA activation as a rotation project.
Minimotif Miner in Science
Release of our Minimotif miner website was covered in Science.